适体
注意事项
食物过敏原
生物技术
食物蛋白
花生酱
食品科学
食品
计算机科学
检测点注意事项
计算生物学
纳米技术
化学
生物
医学
过敏原
材料科学
分子生物学
免疫学
过敏
护理部
作者
Sarah Stidham,Valerie A. Villareal,Vasant Chellappa,Lucas Yoder,Olivia Alley,Wayne G. Shreffler,Jonathan M. Spergel,David M. Fleischer,Hugh A. Sampson,Adi Gilboa-Geffen
标识
DOI:10.1038/s41598-022-05265-0
摘要
Aptamers, due to their small size, strong target affinity, and ease of chemical modification, are ideally suited for molecular detection technologies. Here, we describe successful use of aptamer technology in a consumer device for the detection of peanut antigen in food. The novel aptamer-based protein detection method is robust across a wide variety of food matrices and sensitive to peanut protein at concentrations as low as 12.5 ppm (37.5 µg peanut protein in the sample). Integration of the assay into a sensitive, stable, and consumer friendly portable device will empower users to easily and quickly assess the presence of peanut allergens in foods before eating. With many food reactions occurring outside the home, the type of technology described here has significant potential to improve lives for children and families.
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