This chapter discusses the cause of recurrent pregnancy loss and associated factors and their management. Miscarriages classified on the basis of ultrasound findings into biochemical, empty gestation sac, fetal or second trimester. The management of recurrent miscarriage is challenging because of lack of evidence-based effective treatments. Supportive care has been shown to be beneficial. Women with recurrent miscarriage are anxious and appreciate reassurance when they fall pregnant again. Three-quarters of these women with idiopathic recurrent miscarriage will achieve a live birth in the subsequent pregnancy, with tender loving care involving regular reassurance scans and psychological support in a dedicated early pregnancy assessment unit. Empirical treatment in women with idiopathic recurrent miscarriage should be avoided and entry into high-quality and methodologically sound trials should be considered whenever possible in order to improve the evidence base for this distressing condition.