医学
偏头痛
药物警戒
止痛药
重症监护医学
急性偏头痛
不利影响
药品
非甾体
替代医学
药理学
麻醉学
麻醉
安慰剂
病理
作者
Yulia Orlova,Sandhya Mehla,Abigail L. Chua
标识
DOI:10.1007/s11916-022-01057-3
摘要
The aim of this review is to aid in choosing safe options when assessing potential risks of acute migraine treatments based on known mechanisms of action and anticipated safety concerns.Part 1 highlights safety issues associated with commonly used medications to treat acute migraine attacks. Strategies to mitigate cardiovascular and gastrointestinal risks of nonsteroidal anti-inflammatory drugs, evaluation of cardiovascular risks of triptan and ergot alkaloids, and precautions with use of antiemetics and the novel drugs gepants and ditans are discussed to help practitioners in clinical decision-making. When available, we included recommendations from professional societies and data from pharmacovigilance systems. While guidelines on efficacy are available, one must also consider the possible risks and adverse effects of a drug when creating treatment plans.
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