蛋白尿
医学
内科学
蛋白尿
微量白蛋白尿
糖尿病肾病
肾脏疾病
作者
Montserrat Baldán-Martín,Elena Rodríguez‐Sánchez,Laura González-Calero,Luís M. Ruilope,Gloria Alvarez-Llamas,María G. Barderas,Gema Ruiz‐Hurtado
出处
期刊:Clinical Science
[Portland Press]
日期:2018-04-06
卷期号:132 (7): 739-758
被引量:4
摘要
The development of de novo albuminuria during chronic renin-angiotensin system (RAS) suppression is a clinical entity that remains poorly recognized in the biomedical literature. It represents a clear increment in global cardiovascular (CV) and renal risk that cannot be counteracted by RAS suppression. Although not specifically considered, it is clear that this entity is present in most published and ongoing trials dealing with the different forms of CV and renal disease. In this review, we focus on the mechanisms promoting albuminuria, and the predictors and new markers of de novo albuminuria, as well as the potential treatment options to counteract the excretion of albumin. The increase in risk that accompanies de novo albuminuria supports the search for early markers and predictors that will allow practising physicians to assess and prevent the development of de novo albuminuria in their patients.
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