鱼腥草
山茶
抗氧化剂
化学
传统医学
CYP2E1
乙醇
丙氨酸转氨酶
食品科学
酶
生物
生物化学
植物
细胞色素P450
医学
内分泌学
色谱法
萃取(化学)
作者
Yanghee You,Hyunmi Lee,Ho‐Geun Yoon,Jeongjin Park,Ok‐Kyung Kim,Kyungmi Kim,Min-Jae Lee,Yoo‐Hyun Lee,Jeongmin Lee,Woojin Jun
出处
期刊:Journal of Medicinal Food
[Mary Ann Liebert]
日期:2018-02-01
卷期号:21 (2): 203-206
被引量:6
标识
DOI:10.1089/jmf.2017.4043
摘要
The protective activity of a mixture of aqueous and ethanolic extracts from Houttuynia cordata Thunb, Nelumbo nucifera G. leaves, and Camellia sinensis seed (HNC) was evaluated in C57BL/6 mice. Pretreatment with HNC prevented the elevation of serum aspartate aminotransferase and alanine aminotransferase caused by ethanol-induced hepatic damage. The HNC-treated mice showed significantly lower triglyceride levels, reduced CYP2E1 activity, and increased antioxidant enzyme activities and lipogenic mRNA levels. These results suggest that HNC might be a candidate agent for liver protection against ethanol-induced oxidative damage, through enhancement of antioxidant and antilipogenic activity.
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