脱氧核酶
DNA甲基化
DNA
甲基化
分子生物学
化学
计算生物学
生物
计算机科学
生物化学
基因
基因表达
作者
Mei Li,Lei Zhang,Gangyi Chen,Jing Zhou,Yi Yuan,Jiawei Zou,Mingming Yuan,Rong Chen,Feng Du,Xin Cui,Xin Huang,Juan Dong,Zhuo Tang
摘要
A novel colorimetric method which utilizes DNAzyme as a signal reporter was developed for DNA methylation detection. As low as 1/106 of methylated DNA could be successfully detected from unmethylated DNA. The discrimination ability is at least two orders of magnitude better than that of the methylation specific PCR.
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(2025-6-4)
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