A New Antibacterial Polyketide from the Endophytic Fungi Aspergillus fumigatiaffinis

A new antibacterial polyketide (-) palitantin was isolated from Aspergillus fumigatiaffnis, an endophytic fungi from a medicinal plant Tribulus terestris. The structure of the antibacterial metabolite was established using 1D and 2D NMR together with mass spectroscopy. (-) Palitantin was found to inhibit the growth of Enterococcus faecalis UW 2689 and Streptococcus pneumoniae with MIC value of 64μg/mL.