医学
前臂
假关节
外科
骨合成
骨愈合
骨干
肘部
握力
固定(群体遗传学)
髓内棒
骨科手术
环境卫生
人口
作者
Michael Strassmair,Mont Ma,Thorsten M. Seyler,Hans Bösebeck,Marker Dr,LaPorte Dm
出处
期刊:PubMed
日期:2009-04-01
卷期号:18: 213-8
被引量:1
摘要
The purpose of this study was to assess the use of a novel bone void filler consisting of Type I collagen and various growth factors (VEGF, TGFβ-1, TGFβ-2, IGF-1, BMP-2, BMP-3, and BMP-7) and surgical fixation to treat diaphyseal forearm pseudarthroses. Eleven patients underwent an osteosynthesis procedure for isolated pseudarthrosis fractures of the forearm (six radial and five ulnar diaphysis). The mean duration between the initial failed surgical fixation and re-operation was 38 weeks. Radiographic signs of fracture healing after the application of the bone void filler were noted at a mean of 5 weeks, and complete fracture consolidation was achieved at a mean of 6 weeks. All patients demonstrated improved range of motion and grip strength. Additionally, all patients were pain-free by 6 weeks. The combination of a novel bovine bone-derived bone void filler and stable internal fixation led to union and rapid healing of forearm pseudarthroses.
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