血沉
类风湿性关节炎
医学
内科学
淋巴细胞
血小板
胃肠病学
C反应蛋白
临床意义
免疫学
关节炎
平均血小板体积
炎症
中性粒细胞与淋巴细胞比率
疾病
作者
Hua Fu,Bao-Dong Qin,Zhide Hu,Ning Ma,Min Ye,Tingting Wei,Qingqing Tang,Yuan-Lan Huang,Fenglou Huang,Yan Liu,Zaixing Yang,Renqian Zhong
出处
期刊:Clinical Laboratory
[Clinical Laboratory Publications]
日期:2015-01-01
卷期号:61 (03+04/2015)
被引量:88
标识
DOI:10.7754/clin.lab.2014.140927
摘要
Both neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are reported to be increased in various inflammation-related diseases, but their clinical significance in rheumatoid arthritis (RA) remains unclear. The aim of the present study was to explore whether NLR and PLR were candidate indices for RA disease-activity assessment.The medical records of 128 RA patients and 78 healthy individuals were retrospectively reviewed. Correlations of NLR and PLR with the disease activity of RA were evaluated.NLR and PLR were increased significantly in RA patients. NLR was significantly positively correlated with C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and Disease-Activity Score including 28 joints (DAS28) in RA patients, while PLR was positively correlated with CRP and DAS28, but not with ESR.Both NLR and PLR values may prove to be potential indices for RA disease-activity assessment.
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