医学
精密医学
个性化医疗
循环肿瘤DNA
循环肿瘤细胞
航向(导航)
癌症
生物信息学
肿瘤科
内科学
病理
转移
大地测量学
生物
地理
作者
Izhar Singh Batth,Abhisek Mitra,Salomon Manier,Irene M. Ghobrial,David G. Menter,Scott Kopetz,S. Li
标识
DOI:10.1093/annonc/mdw619
摘要
Current trajectory of clinical care is heading in the direction of personalized medicine. In an ideal scenario, clinicians can obtain extensive diagnostic and prognostic information via minimally-invasive assays. Information available in the peripheral blood has the potential to bring us closer to this goal. In this review we highlight the contributions of circulating tumor cells and circulating tumor DNA and RNA (ctDNA/ctRNA) towards cancer therapeutic field. We discuss clinical relevance, summarize available and upcoming technologies, and hypothesize how future care could be impacted by a combined study.
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