Deoxygenation of Ethers To Form Carbon–Carbon Bonds via Nickel Catalysis

In this article a successful protocol was developed to construct carbon–carbon bonds by the extrusion of the O atom of ethers via nickel catalysis in the presence of reductants. This methodology is featured as a highly economic route to construct sp3–sp3 C–C bonds through dual C–O activation of ethers with good functional group tolerance.