Determination of mineral oil residues in chicken's kidney by GC-MS

Objective To determine the residues of mineral oil components in the chicken's kidney and to investigate the metabolic changes of mineral oil components in a simulated vaccination model.Methods Chickens of 15-day-old were injected im with white oil No.7(a commercially available mineral oil adjuvant) and the residues of oil components in kidney were determined using GC-MS method on the d 3,d 7,d 14,d 28,and d 56 after injection.Results It was found that on d 3 after the injection,10 alkanes were detected among the 11 alkanes detected in white oil No.7 in the kidney,and on d 56 after injection there were still 6 alkanes detected in the kidney.Conclusion The results showed that the mineral oil reached the kidney via circulation,and using mineral oil as an adjuvant in food production of animal origin might bring some safety risks.