Association of Life's Simple 7 with mild cognitive impairment in community-dwelling older adults in China: a cross-sectional study

逻辑回归 置信区间 医学 痴呆 老年学 人口学 共病 联想(心理学) 横断面研究 内科学 疾病 物理疗法 心理学 病理 社会学 心理治疗师
作者
Mengshu Yang,Yunning Liu,Xiuzhen Hu,Dianxu Ren,Qing Yang,Jing Mao,Jing Chen
出处
期刊:Frontiers in Aging Neuroscience [Frontiers Media]
卷期号:15
标识
DOI:10.3389/fnagi.2023.1203920
摘要

Life's Simple 7 (LS7), a metric composed of seven intervenable cardiovascular risk factors, is initiated by the American Heart Association to improve cardiovascular health. The components of LS7 have been reported as risk factors for dementia. However, few studies investigated the association between LS7 metric and mild cognitive impairment (MCI).The study was carried out in a primary care facility between 8 June and 10 July 2022. A total of 297 community-dwelling residents aged 65 years or older were recruited. Sociodemographic, comorbidity, and lifestyle characteristics were collected through the questionnaires, and biological parameters were obtained from blood sample examinations. Logistic regression was used to analyze the association between LS7 scores (overall, behavioral, and biological) and individual components with MCI, adjusting sex, age, education, and cardiovascular disease (CVD).In comparison with the cognitively intact group (n = 195), the MCI group (n = 102) had a lower education level and a higher proportion of hypertension. Multivariate logistic regression analysis, adjusting sex, age, education, and CVD demonstrated a significant association between MCI and overall LS7 score [odd ratio = 0.805, 95% confidence interval (0.690, 0.939)] and biological score [odd ratio = 0.762, 95% confidence interval (0.602, 0.965)].Life's Simple 7 was associated with MCI in community-dwelling older adults, indicating that LS7 could be used as guidance in the prevention of dementia in the community.

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