再生(生物学)
医学
血管生成
血运重建
治疗性血管生成
疾病
纳米医学
血管疾病
神经科学
生物信息学
新生血管
病理
癌症研究
外科
生物
心脏病学
纳米技术
心肌梗塞
纳米颗粒
细胞生物学
材料科学
作者
Xinyue Chen,Wenlu Yu,Jing Zhang,Xuetong Fan,Xiao Liu,Qi Liu,Su Pan,Richard A. F. Dixon,Pengyang Li,Peng Yu,Ao Shi
标识
DOI:10.1186/s13036-023-00330-2
摘要
Ischemic vascular disease is a major healthcare problem. The keys to treatment lie in vascular regeneration and restoration of perfusion. However, current treatments cannot satisfy the need for vascular regeneration to restore blood circulation. As biomedical research has evolved rapidly, a variety of potential alternative therapeutics has been explored widely, such as growth factor-based therapy, cell-based therapy, and material-based therapy including nanomedicine and biomaterials. This review will comprehensively describe the main pathogenesis of vascular injury in ischemic vascular disease, the therapeutic function of the above three treatment strategies, the corresponding potential challenges, and future research directions.
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