波形蛋白
癌症研究
细胞培养
肿瘤微环境
基质
胰腺癌
生物
基因表达
癌相关成纤维细胞
癌症
肿瘤进展
间质细胞
遗传异质性
腺癌
胰腺肿瘤
基因
病理
医学
免疫组织化学
表型
免疫学
遗传学
肿瘤细胞
作者
Joseph F. Kearney,Hannah E. Trembath,P. Chan,Ashley B. Morrison,Yi Xu,Chang Fei Luan,Ian C. McCabe,Sandra Zarmer,Han Jo Kim,Xianlu L. Peng,Jen Jen Yeh
摘要
Pancreatic ductal adenocarcinoma (PDAC) has a fibrotic stroma that has both tumor-promoting and tumor-restraining properties. Different types of cancer-associated fibroblasts (CAFs) have been described. Here, we investigated whether CAFs within the same subtype exhibit heterogeneous functions.
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