Treatment Outcome of Response-based Radiotherapy in Children and Adolescents with Central Nervous System Nongerminomatous Germ Cell Tumors: Result of a Prospective Study

The optimal dose and range of radiation therapy for central nervous system nongerminomatous germ cell tumors (NGGCTs) have not been uniformly established. Therefore, this study aimed to investigate the effect of individualized radiation therapy, based on the response to induction chemotherapy combined with surgery, on the prognosis of patients with NGGCTs.