Enhancement in Biological Availability of Vitamins by Nano-engineering and its Applications: An Update

纳米技术 生物利用度 纳米结构 纳米材料 药物输送 纳米颗粒 材料科学 生化工程 生物信息学 工程类 生物
作者
Sadhna Mishra,Shalini Sahani,Shikha Pandhi,Arvind Kumar,Dipendra Kumar Mahato,Pradeep Kumar,Kaustubh Chandrakant Khaire,Ashutosh Rai
出处
期刊:Current Pharmaceutical Biotechnology [Bentham Science]
卷期号:25 (12): 1523-1537 被引量:2
标识
DOI:10.2174/0113892010251234231025085759
摘要

Abstract:: Vitamin nano-engineering has been accomplished by synthesizing various nanostructures to improve their stability, bioavailability, shelf life, and functioning. This review provides a detailed description of recent advances in the art of encapsulation with high efficiency through the use of practical and logistic nano-engineering techniques such as nanofibres, nanogels, nanobeads, nanotubes, nanoparticles, nanoliposomes, and many other nanostructures. To demonstrate the interaction of molecules with nano-forms, the bioavailability of several vitamins such as B, C, E, A, D, and others in the form of nanostructures is explored. This review will provide a thorough understanding of how to improve bioavailability and nanostructure selection to extend the utility, shelf life, and structural stability of vitamins. While nanoencapsulation can improve vitamin stability and distribution, the materials employed in nanotechnologies may offer concerns if they are not sufficiently tested for safety. If nanoparticles are not adequately designed and evaluated, they may cause inflammation, oxidative stress, or other unwanted effects. Researchers and makers of nanomaterials and medication delivery systems should adhere to established rules and regulations. Furthermore, long-term studies are required to monitor any negative consequences that may result from the use of nanostructure.
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