Prostate Biopsy Culture Findings of Men With Chronic Pelvic Pain Syndrome do Not Differ From Those of Healthy Controls

No AccessJournal of UrologyCLINICAL UROLOGY: Original Articles1 Feb 2003Prostate Biopsy Culture Findings of Men With Chronic Pelvic Pain Syndrome do Not Differ From Those of Healthy Controls JAY C. LEE, CHARLES H. MULLER, IVAN ROTHMAN, KATHY J. AGNEW, DAVID ESCHENBACH, MARCIA A. CIOL, JUDITH A. TURNER, and RICHARD E. BERGER JAY C. LEEJAY C. LEE , CHARLES H. MULLERCHARLES H. MULLER , IVAN ROTHMANIVAN ROTHMAN , KATHY J. AGNEWKATHY J. AGNEW , DAVID ESCHENBACHDAVID ESCHENBACH , MARCIA A. CIOLMARCIA A. CIOL , JUDITH A. TURNERJUDITH A. TURNER , and RICHARD E. BERGERRICHARD E. BERGER View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)63958-4AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: Previous reports have identified bacteria in the prostate of men with chronic pelvic pain syndrome. To examine whether prostatic bacteria are more prevalent among patients with chronic pelvic pain syndrome than among those without pelvic pain, we compared 4-glass urine test and prostate biopsy results. Materials and Methods: A total of 120 patients with types IIIa and IIIb chronic pelvic pain syndrome and 60 asymptomatic controls underwent a standard 4-glass urine test, examination of expressed prostatic secretion leukocytes by hemocytometer and transperineal, digitally guided prostate biopsies. Tissue was cultured for aerobes, anaerobes, Trichomonas vaginalis, Chlamydia trachomatis and herpes simplex virus. Skin cultures were performed on a subset of patients and controls. Results: Positive prostate biopsy cultures were obtained from patients and controls. Bacteria were found in 45 of 118 pain patients (38%) and in 21 of 59 controls (36%) (p = 0.74). Older men were more likely to have positive cultures. Men with type IIIa chronic pelvic pain syndrome were more likely than those with type IIIb to have positive prostate biopsy cultures. Conclusions: Bacteria cultured from transperineal prostatic biopsies do not differ between men with and without chronic pelvic pain syndrome. Prostatic bacteria obtained by biopsy are probably not etiologically related to the symptoms in the majority of men with chronic pelvic pain syndrome. References 1 : How common is prostatitis? A national survey of physician visits. J Urol1998; 159: 1224. Link, Google Scholar 2 : Diagnosis and treatment of 409 patients with prostatitis syndromes. Urology1993; 41: 301. Crossref, Medline, Google Scholar 3 : Research guidelines for chronic prostatitis: consensus report from the first National Institutes of Health International Prostatitis Collaborative Network. Urology1999; 54: 229. Crossref, Medline, Google Scholar 4 : Bacteriologic localization patterns in bacterial prostatitis and urethritis. 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Google Scholar From the Departments of Urology, Obstetrics and Gynecology, Rehabilitation Medicine, and Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington© 2003 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited byCOHEN R, SHANNON B, McNEAL J, SHANNON T and GARRETT K (2018) PROPIONIBACTERIUM ACNES ASSOCIATED WITH INFLAMMATION IN RADICAL PROSTATECTOMY SPECIMENS: A POSSIBLE LINK TO CANCER EVOLUTION?Journal of Urology, VOL. 173, NO. 6, (1969-1974), Online publication date: 1-Jun-2005.KRIEGER J and RILEY D (2018) CHRONIC PROSTATITIS: CHARLOTTESVILLE TO SEATTLEJournal of Urology, VOL. 172, NO. 6 Part 2, (2557-2560), Online publication date: 1-Dec-2004. Volume 169 Issue 2 February 2003 Page: 584-588 Advertisement Copyright & Permissions© 2003 by American Urological Association, Inc.Keywordsprostatitiscase-control studiesbiopsypelvic painbacteriaMetrics Author Information JAY C. LEE Financial interest and/or other relationship with Bayer, Pfizer, Lilly and Janssen Ortho. More articles by this author CHARLES H. MULLER More articles by this author IVAN ROTHMAN Financial interest and/or other relationship with Pfizer. More articles by this author KATHY J. AGNEW More articles by this author DAVID ESCHENBACH Financial interest and/or other relationship with 3M and Pharmacia. More articles by this author MARCIA A. CIOL More articles by this author JUDITH A. TURNER More articles by this author RICHARD E. BERGER More articles by this author Expand All Advertisement PDF downloadLoading ...