Effects of dietary oxidized fish oil on growth performance, antioxidant defense system, apoptosis and mitochondrial function of juvenile largemouth bass (Micropterus salmoides)

生物 微翅目 鲈鱼(鱼) 鱼油 脂质过氧化 谷胱甘肽过氧化物酶 抗氧化剂 超氧化物歧化酶 动物科学 生物化学 食品科学 内分泌学 渔业
作者
Peng Yin,Shiwei Xie,Yunjing Huo,Tianyu Guo,HaoHang Fang,Yan‐Mei Zhang,Yongjian Liu,Lixia Tian,Jin Niu
出处
期刊:Aquaculture [Elsevier BV]
卷期号:500: 347-358 被引量:65
标识
DOI:10.1016/j.aquaculture.2018.09.009
摘要

Four isonitrogenous and isolipidic diets containing fresh fish oil (peroxide value, POV: 7.2 meq kg−1, diet FR) and three degrees of oxidized fish oil (POV: 155, 275 and 564 meq kg−1, diet OX155, OX275 and OX564, respectively) were formulated to investigate the effects of dietary oxidized fish oil on growth performance, body composition, antioxidant defense system and mitochondrial function of juvenile largemouth bass, Micropterus salmoides. After a 12-week feeding trial, fish fed the OX155 obtained significantly higher (P < .05) weight gain, final body weight and specific growth rate than the FR because of their remarkable higher feed intake. Malonaldehyde (MDA) levels were markedly increased in plasma, liver and mitochondria of largemouth bass fed diet OX564 than those fed FR. Fish fed the OX564 also obtained the highest levels of lipid peroxidation (LPO) than other groups. Antioxidant enzyme activities and mRNA levels were stimulated after 12 weeks of feeding. The highest activities of superoxide dismutase (SOD) and glutathione peroxidase (Gpx) in liver and plasma were obtained in group OX564. The relative expression of TNF-α was decreased with the increasing oxidative degree of dietary fish oil, while the relative expression of Caspase 8, 9 and 10 were increased with the increasing oxidative degree of dietary fish oil. The relative expression of Bcl-2 and Bcl-xL were lower in fish fed the OX275 and OX564. The lowest activities of malate dehydrogenase (MDH), succinate dehydrogenase (SDH) and citrate synthase in liver were found in group OX564, in which the ATP level also lower than other groups. Liver mitochondria of fish fed the FR were more resistant to the calcium-induced mitochondrial swelling. More reactive oxygen species (ROS) were produced in fish fed the OX564 compared with those fed the FR after the 12-week trial. Membrane potential and Ca2+ induced swelling of mitochondria also affected by dietary oxidized fish oil. The present study indicated that dietary oxidized fish oil increased oxidative stress, influenced antioxidant system and induced apoptosis of largemouth bass, hepatic mitochondrial function and energy metabolism also were impaired by dietary oxidized fish oil.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
乔苏惠娜完成签到,获得积分10
刚刚
刚刚
Yyy完成签到,获得积分10
刚刚
鸭梨完成签到,获得积分10
1秒前
打打应助安详蜜蜂采纳,获得10
1秒前
1秒前
xinyuY完成签到,获得积分10
1秒前
凉雨街完成签到,获得积分10
1秒前
su完成签到,获得积分10
2秒前
xxxxx发布了新的文献求助10
2秒前
2秒前
慕青应助王怡采纳,获得10
3秒前
愉快的皮卡丘完成签到 ,获得积分10
3秒前
cute666发布了新的文献求助10
3秒前
可以理解发布了新的文献求助10
3秒前
3秒前
Hey完成签到 ,获得积分10
3秒前
韩野完成签到,获得积分10
4秒前
7弥LY完成签到 ,获得积分10
4秒前
4秒前
4秒前
辛辛那提完成签到,获得积分10
4秒前
5秒前
丁仪发布了新的文献求助10
5秒前
6秒前
凉雨街发布了新的文献求助10
6秒前
6秒前
7秒前
hui发布了新的文献求助10
7秒前
7秒前
球球尧伞耳完成签到,获得积分10
8秒前
钮卿完成签到 ,获得积分10
9秒前
9秒前
无私的颤完成签到,获得积分10
9秒前
我是老大应助xxxxx采纳,获得10
9秒前
苏哼哼发布了新的文献求助10
9秒前
9秒前
小郭小郭福气多多完成签到,获得积分10
9秒前
单身的世倌完成签到,获得积分20
9秒前
高分求助中
(应助此贴封号)【重要!!请各用户(尤其是新用户)详细阅读】【科研通的精品贴汇总】 10000
网络安全 SEMI 标准 ( SEMI E187, SEMI E188 and SEMI E191.) 1000
计划经济时代的工厂管理与工人状况(1949-1966)——以郑州市国营工厂为例 500
INQUIRY-BASED PEDAGOGY TO SUPPORT STEM LEARNING AND 21ST CENTURY SKILLS: PREPARING NEW TEACHERS TO IMPLEMENT PROJECT AND PROBLEM-BASED LEARNING 500
Why America Can't Retrench (And How it Might) 400
Two New β-Class Milbemycins from Streptomyces bingchenggensis: Fermentation, Isolation, Structure Elucidation and Biological Properties 300
Modern Britain, 1750 to the Present (第2版) 300
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 纳米技术 计算机科学 内科学 化学工程 复合材料 物理化学 基因 催化作用 遗传学 冶金 电极 光电子学
热门帖子
关注 科研通微信公众号,转发送积分 4614581
求助须知:如何正确求助?哪些是违规求助? 4018748
关于积分的说明 12439646
捐赠科研通 3701503
什么是DOI,文献DOI怎么找? 2041241
邀请新用户注册赠送积分活动 1073983
科研通“疑难数据库(出版商)”最低求助积分说明 957639