Recent demography drives changes in linked selection across the maize genome

驯化 生物 有效人口规模 选择(遗传算法) 人口 人口瓶颈 群体基因组学 遗传多样性 否定选择 遗传漂变 人口规模 人口历史 进化生物学 基因组 遗传变异 基因组学 遗传学 等位基因 人口学 基因 微卫星 人工智能 社会学 计算机科学
作者
Timothy Beissinger,Li Wang,Kate Crosby,Arun Durvasula,Matthew B. Hufford,Jeffrey Ross‐Ibarra
出处
期刊:Nature plants [Nature Portfolio]
卷期号:2 (7) 被引量:115
标识
DOI:10.1038/nplants.2016.84
摘要

Genetic diversity is shaped by the interaction of drift and selection, but the details of this interaction are not well understood. The impact of genetic drift in a population is largely determined by its demographic history, typically summarized by its long-term effective population size (Ne). Rapidly changing population demographics complicate this relationship, however. To better understand how changing demography impacts selection, we used whole-genome sequencing data to investigate patterns of linked selection in domesticated and wild maize (teosinte). We produce the first whole-genome estimate of the demography of maize domestication, showing that maize was reduced to approximately 5% the population size of teosinte before it experienced rapid expansion post-domestication to population sizes much larger than its ancestor. Evaluation of patterns of nucleotide diversity in and near genes shows little evidence of selection on beneficial amino acid substitutions, and that the domestication bottleneck led to a decline in the efficiency of purifying selection in maize. Young alleles, however, show evidence of much stronger purifying selection in maize, reflecting the much larger effective size of present day populations. Our results demonstrate that recent demographic change—a hall-mark of many species including both humans and crops—can have immediate and wide-ranging impacts on diversity that conflict with expectations based on long-term Ne alone. A study using population genomic data of domesticated and wild maize shows that purifying selection plays a major role in shaping maize diversity, and the efficacy of purifying selection increased following post-domestication population expansion.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
1秒前
FIN应助小小采纳,获得30
1秒前
领导范儿应助su采纳,获得10
2秒前
Candy发布了新的文献求助10
2秒前
Rondab应助xiaosu采纳,获得10
3秒前
CodeCraft应助LJJ采纳,获得10
4秒前
4秒前
SYLH应助科研通管家采纳,获得20
5秒前
所所应助科研通管家采纳,获得10
5秒前
科研通AI5应助科研通管家采纳,获得10
5秒前
张金蝶完成签到,获得积分10
5秒前
搜集达人应助科研通管家采纳,获得10
6秒前
CAOHOU应助科研通管家采纳,获得10
6秒前
丘比特应助科研通管家采纳,获得10
6秒前
CAOHOU应助科研通管家采纳,获得10
6秒前
赘婿应助科研通管家采纳,获得10
6秒前
量子星尘发布了新的文献求助30
6秒前
SYLH应助科研通管家采纳,获得20
6秒前
6秒前
6秒前
6秒前
CAOHOU应助科研通管家采纳,获得10
6秒前
Lyuhng+1完成签到 ,获得积分10
7秒前
大个应助十九岁的时差采纳,获得10
8秒前
11秒前
桃花落完成签到,获得积分10
14秒前
su发布了新的文献求助10
14秒前
思源应助汪汪采纳,获得10
14秒前
高兴的天蓝完成签到 ,获得积分10
15秒前
15秒前
16秒前
星星应助momo采纳,获得10
16秒前
17秒前
阿钉发布了新的文献求助10
18秒前
科研通AI2S应助愉快的宛儿采纳,获得10
18秒前
19秒前
LJJ发布了新的文献求助10
22秒前
Simlove完成签到,获得积分10
23秒前
高贵魂幽完成签到,获得积分10
23秒前
ccygpp199发布了新的文献求助10
25秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3989334
求助须知:如何正确求助?哪些是违规求助? 3531428
关于积分的说明 11253936
捐赠科研通 3270119
什么是DOI,文献DOI怎么找? 1804887
邀请新用户注册赠送积分活动 882087
科研通“疑难数据库(出版商)”最低求助积分说明 809173