This presentation will explore 3 novel treatments for ASD using placebo comparators. Additional treatment options are needed for children with ASD and it may be necessary to subgroup for specific treatments. Some children with ASD have low cholesterol, which is necessary for normal brain development. Many people with ASD have gastrointestinal (GI) dysfunction, possibly with abnormal gut flora. Essential oils have been reported to be anecdotally helpful by caregivers for anxiety.