An AIE-active theranostic probe for light-up detection of Aβ aggregates and protection of neuronal cells

An AIE-active probe of Cur-N-BF₂ is developed for light-up detection of Aβ fibrils and plaques, inhibition of Aβ fibrillation, disassembly of preformed Aβ fibrils, and protection of neuronal cells.