肌阵挛
神经化学
神经科学
医学
视索克隆
心理学
生物
神经母细胞瘤
遗传学
细胞培养
作者
Michael R. Pranzatelli
出处
期刊:Clinical Neuropharmacology
[Ovid Technologies (Wolters Kluwer)]
日期:1992-06-01
卷期号:15 (3): 186-228
被引量:202
标识
DOI:10.1097/00002826-199206000-00002
摘要
Opsoclonus-myoclonus is a pervasive neurological syndrome of children and adults. Although rare, it raises important clinical and neurobiological issues. This article provides an overview of the clinical and laboratory features, differential diagnosis, treatment, and outcome of opsoclonus-myoclonus. It pursues immunologie, genetic, electrophysiologic, neurochemical, and other clues to a pharmacologic model. Key questions include how and where the brain is injured, reversibility of the injury, possible targets for pharmacologie intervention, and which new studies are needed.
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