Roles of IGH and L Chains and of Surrogate H and L Chains in the Development of Cells of the B Lymphocyte Lineage
B细胞
B细胞受体
幼稚B细胞
抗原
生发中心
T细胞
免疫球蛋白轻链
细胞生物学
免疫球蛋白重链
作者
Fritz Melchers,Dirk Haasner,Uif Grawunder,Christian Kalberer,Hajime Karasuyama,Thomas Winkler,Antonius Rolink
出处
期刊:Annual Review of Immunology [Annual Reviews] 日期:1994-01-01卷期号:12 (1): 209-225被引量:112
标识
DOI:10.1146/annurev.iy.12.040194.001233
摘要
Proteins expressed from productively rearranged Hand L chain gene loci have been implied in the regulation of Ig gene rearrangements during B lymphopoiesis. However, recent findings suggest that early