亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

A Model for Predicting the Risk of De Novo Stress Urinary Incontinence in Women Undergoing Pelvic Organ Prolapse Surgery

医学 吊索(武器) 尿失禁 一致性 置信区间 逻辑回归 外科 泌尿系统 压力性尿失禁 列线图 泌尿科 妇科 内科学
作者
J. Eric Jelovsek,Kevin Chagin,Linda Brubaker,Rebecca G. Rogers,Holly E. Richter,Lily A. Arya,Matthew D. Barber,Jonathan P. Shepherd,Tracy L. Nolen,Peggy Norton,Vivian W. Sung,Shawn A. Menefee,Nazema Y. Siddiqui,Susan Meikle,Michael W. Kattan
出处
期刊:Obstetrics & Gynecology [Lippincott Williams & Wilkins]
卷期号:123 (2): 279-287 被引量:70
标识
DOI:10.1097/aog.0000000000000094
摘要

In Brief OBJECTIVE: To construct and validate a prediction model for estimating the risk of de novo stress urinary incontinence (SUI) after vaginal pelvic organ prolapse (POP) surgery and compare it with predictions using preoperative urinary stress testing and expert surgeons' predictions. MATERIALS AND METHODS: Using the data set (n=457) from the Outcomes Following Vaginal Prolapse Repair and Midurethral Sling trial, a model using 12 clinical preoperative predictors of de novo SUI was constructed. De novo SUI was determined by Pelvic Floor Distress Inventory responses through 12 months postoperatively. After fitting the multivariable logistic regression model using the best predictors, the model was internally validated with 1,000 bootstrap samples to obtain bias-corrected accuracy using a concordance index. The model's predictions were also externally validated by comparing findings against actual outcomes using Colpopexy and Urinary Reduction Efforts trial patients (n=316). The final model's performance was compared with experts using a test data set of 32 randomly chosen Outcomes Following Vaginal Prolapse Repair and Midurethral Sling trial patients through comparison of the model's area under the curve against: 1) 22 experts' predictions; and 2) preoperative prolapse reduction stress testing. RESULTS: A model containing seven predictors discriminated between de novo SUI status (concordance index 0.73, 95% confidence interval [CI] 0.65–0.80) in Outcomes Following Vaginal Prolapse Repair and Midurethral Sling participants and outperformed expert clinicians (area under the curve 0.72 compared with 0.62, P<.001) and preoperative urinary stress testing (area under the curve 0.72 compared with 0.54, P<.001). The concordance index for Colpopexy and Urinary Reduction Efforts trial participants was 0.62 (95% CI 0.56–0.69). CONCLUSION: This individualized prediction model for de novo SUI after vaginal POP surgery is valid and outperforms preoperative stress testing, prediction by experts, and preoperative reduction cough stress testing. An online calculator is provided for clinical use. LEVEL OF EVIDENCE: III A valid, individualized prediction model for de novo stress urinary incontinence after vaginal pelvic organ prolapse surgery outperforms preoperative stress testing and expert prediction.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
积极的台灯完成签到,获得积分10
12秒前
紫荆完成签到,获得积分10
15秒前
Johnson完成签到 ,获得积分10
25秒前
李健应助科研通管家采纳,获得10
39秒前
Benhnhk21发布了新的文献求助10
50秒前
wanci应助淡然绝山采纳,获得10
54秒前
1分钟前
wkjfh应助YaoQi采纳,获得10
2分钟前
dyuguo3完成签到 ,获得积分10
2分钟前
某某某发布了新的文献求助10
2分钟前
2分钟前
淡然绝山发布了新的文献求助10
2分钟前
Benhnhk21完成签到,获得积分10
2分钟前
JamesPei应助andrele采纳,获得10
2分钟前
完美世界应助xiongdi521采纳,获得10
3分钟前
3分钟前
3分钟前
xiongdi521发布了新的文献求助10
3分钟前
3分钟前
xiao涂完成签到,获得积分10
4分钟前
4分钟前
闫雪发布了新的文献求助10
4分钟前
打打应助闫雪采纳,获得10
4分钟前
吗喽完成签到,获得积分10
4分钟前
某某某完成签到,获得积分10
4分钟前
5分钟前
爱吃橙子完成签到 ,获得积分10
5分钟前
丰富莹芝发布了新的文献求助10
5分钟前
思源应助丰富莹芝采纳,获得10
5分钟前
Akitten发布了新的文献求助10
5分钟前
qqq完成签到,获得积分10
5分钟前
5分钟前
小博发布了新的文献求助10
6分钟前
童大大完成签到,获得积分20
6分钟前
小博完成签到,获得积分10
6分钟前
CodeCraft应助糯糯采纳,获得10
6分钟前
汉堡包应助Plum22采纳,获得10
7分钟前
岁岁完成签到 ,获得积分10
7分钟前
7分钟前
Plum22发布了新的文献求助10
8分钟前
高分求助中
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3990171
求助须知:如何正确求助?哪些是违规求助? 3532136
关于积分的说明 11256472
捐赠科研通 3271042
什么是DOI,文献DOI怎么找? 1805171
邀请新用户注册赠送积分活动 882302
科研通“疑难数据库(出版商)”最低求助积分说明 809234