清晨好,您是今天最早来到科研通的研友!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您科研之路漫漫前行!

A Model for Predicting the Risk of De Novo Stress Urinary Incontinence in Women Undergoing Pelvic Organ Prolapse Surgery

医学 吊索(武器) 尿失禁 一致性 置信区间 逻辑回归 外科 泌尿系统 压力性尿失禁 列线图 泌尿科 妇科 内科学
作者
J. Eric Jelovsek,Kevin Chagin,Linda Brubaker,Rebecca G. Rogers,Holly E. Richter,Lily A. Arya,Matthew D. Barber,Jonathan P. Shepherd,Tracy L. Nolen,Peggy Norton,Vivian W. Sung,Shawn A. Menefee,Nazema Y. Siddiqui,Susan Meikle,Michael W. Kattan
出处
期刊:Obstetrics & Gynecology [Lippincott Williams & Wilkins]
卷期号:123 (2): 279-287 被引量:70
标识
DOI:10.1097/aog.0000000000000094
摘要

In Brief OBJECTIVE: To construct and validate a prediction model for estimating the risk of de novo stress urinary incontinence (SUI) after vaginal pelvic organ prolapse (POP) surgery and compare it with predictions using preoperative urinary stress testing and expert surgeons' predictions. MATERIALS AND METHODS: Using the data set (n=457) from the Outcomes Following Vaginal Prolapse Repair and Midurethral Sling trial, a model using 12 clinical preoperative predictors of de novo SUI was constructed. De novo SUI was determined by Pelvic Floor Distress Inventory responses through 12 months postoperatively. After fitting the multivariable logistic regression model using the best predictors, the model was internally validated with 1,000 bootstrap samples to obtain bias-corrected accuracy using a concordance index. The model's predictions were also externally validated by comparing findings against actual outcomes using Colpopexy and Urinary Reduction Efforts trial patients (n=316). The final model's performance was compared with experts using a test data set of 32 randomly chosen Outcomes Following Vaginal Prolapse Repair and Midurethral Sling trial patients through comparison of the model's area under the curve against: 1) 22 experts' predictions; and 2) preoperative prolapse reduction stress testing. RESULTS: A model containing seven predictors discriminated between de novo SUI status (concordance index 0.73, 95% confidence interval [CI] 0.65–0.80) in Outcomes Following Vaginal Prolapse Repair and Midurethral Sling participants and outperformed expert clinicians (area under the curve 0.72 compared with 0.62, P<.001) and preoperative urinary stress testing (area under the curve 0.72 compared with 0.54, P<.001). The concordance index for Colpopexy and Urinary Reduction Efforts trial participants was 0.62 (95% CI 0.56–0.69). CONCLUSION: This individualized prediction model for de novo SUI after vaginal POP surgery is valid and outperforms preoperative stress testing, prediction by experts, and preoperative reduction cough stress testing. An online calculator is provided for clinical use. LEVEL OF EVIDENCE: III A valid, individualized prediction model for de novo stress urinary incontinence after vaginal pelvic organ prolapse surgery outperforms preoperative stress testing and expert prediction.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
脑洞疼应助科研通管家采纳,获得10
3秒前
顾矜应助科研通管家采纳,获得10
3秒前
wjx完成签到 ,获得积分10
4秒前
John完成签到,获得积分10
15秒前
顾矜应助ceeray23采纳,获得20
26秒前
58秒前
Able完成签到,获得积分10
59秒前
我是笨蛋完成签到 ,获得积分10
1分钟前
ceeray23发布了新的文献求助20
1分钟前
Owen应助董可以采纳,获得10
1分钟前
酷酷妙梦完成签到,获得积分10
1分钟前
科研通AI2S应助彦嘉采纳,获得10
1分钟前
小二郎应助科研通管家采纳,获得10
2分钟前
hhh2018687完成签到,获得积分10
2分钟前
科研通AI2S应助ceeray23采纳,获得20
2分钟前
忘忧Aquarius完成签到,获得积分10
2分钟前
wujiwuhui完成签到 ,获得积分10
2分钟前
Lny发布了新的文献求助30
2分钟前
sh1ro完成签到,获得积分10
2分钟前
luang应助ceeray23采纳,获得40
2分钟前
3分钟前
ww完成签到,获得积分10
3分钟前
斯文败类应助ceeray23采纳,获得20
3分钟前
机智秋莲发布了新的文献求助20
3分钟前
ChatGPT完成签到,获得积分10
3分钟前
所所应助科研通管家采纳,获得10
4分钟前
4分钟前
4分钟前
ceeray23发布了新的文献求助20
4分钟前
海阔天空完成签到 ,获得积分10
4分钟前
zys发布了新的文献求助10
4分钟前
ffdhdh应助LYZSh采纳,获得10
5分钟前
5分钟前
机智秋莲完成签到,获得积分20
5分钟前
欣欣子完成签到 ,获得积分10
5分钟前
apt完成签到 ,获得积分10
5分钟前
科研通AI2S应助科研通管家采纳,获得10
6分钟前
6分钟前
董可以发布了新的文献求助10
7分钟前
Orange应助董可以采纳,获得10
7分钟前
高分求助中
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3990543
求助须知:如何正确求助?哪些是违规求助? 3532220
关于积分的说明 11256532
捐赠科研通 3271057
什么是DOI,文献DOI怎么找? 1805207
邀请新用户注册赠送积分活动 882302
科研通“疑难数据库(出版商)”最低求助积分说明 809234