嗅觉系统
嗅觉
萧条(经济学)
抗抑郁药
神经科学
嗅觉记忆
感觉系统
抑郁症动物模型
心理学
医学
中枢神经系统
嗅球
海马体
经济
宏观经济学
作者
Ti‐Fei Yuan,Burton M. Slotnick
标识
DOI:10.1016/j.pnpbp.2014.05.013
摘要
The olfactory system is involved in sensory functions, emotional regulation and memory formation. Olfactory bulbectomy in rat has been employed as an animal model of depression for antidepressant discovery studies for many years. Olfaction is impaired in animals suffering from chronic stress, and patients with clinical depression were reported to have decreased olfactory function. It is believed that the neurobiological bases of depression might include dysfunction in the olfactory system. Further, brain stimulation, including nasal based drug delivery could provide novel therapies for management of depression.
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