医学
神经营养因子
神经营养素
角膜炎
疾病
神经生长因子
眼科
神经科学
病理
心理学
内科学
受体
作者
Samir Jabbour,Christopher Ashton,Shafi Balal,Abigail Kaye,Sajjad Ahmad
出处
期刊:Current Opinion in Ophthalmology
[Ovid Technologies (Wolters Kluwer)]
日期:2021-05-06
卷期号:32 (4): 362-368
被引量:12
标识
DOI:10.1097/icu.0000000000000766
摘要
Purpose of review The management of neurotrophic keratitis (NK) has evolved in the last decade. The present article reviews updated management guidelines of this entity, as well as future innovations in the field. Recent findings The advent of confocal microscopy has allowed for the first time to image corneal nerves. In addition, multiple novel topical treatments such as nerve growth factor have improved the prognosis of this disease, with many other in the pipeline. Finally, corneal nerve restoration is now possible with corneal neurotization procedures. Summary Many novel treatments based on agents that stimulate nerve regrowth are now available to treat NK. Improvement in neurotization procedures could also address advanced stages of this disease with surgery.
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