哺乳期
生物
初乳
小桶
蛋白质组学
脂质代谢
繁殖
脂肪球
新陈代谢
生物化学
食品科学
转录组
动物科学
乳脂
基因
基因表达
遗传学
抗体
怀孕
亚麻籽油
作者
Wei Jia,Rong Zhang,Zhenbao Zhu,Lin Shi
标识
DOI:10.3389/fnut.2021.680683
摘要
Large variations in the bioactivities and composition of milk fat globule membrane (MFGM) proteins were observed between Saanen dairy goat and Holstein bovine at various lactation periods. In the present study, 331, 250, 182, and 248 MFGM proteins were characterized in colostrum and mature milk for the two species by Q-Orbitrap HRMS-based proteomics techniques. KEGG pathway analyses displayed that differentially expressed proteins in colostrum involved in galactose metabolism and an adipogenesis pathway, and the differentially expressed proteins in mature milk associated with lipid metabolism and a PPAR signaling pathway. These results indicated that the types and functions of MFGM proteins in goat and bovine milk were different, and goat milk had a better function of fatty acid metabolism and glucose homeostasis, which can enhance our understanding of MFGM proteins in these two species across different lactation periods, and they provide significant information for the study of lipid metabolism and glycometabolism of goat milk.
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