医学
转移
骨转移
子宫颈
宫颈癌
放射科
病变
活检
癌症
化疗
肱骨
癌
阶段(地层学)
外科
病理
内科学
古生物学
生物
作者
Alessandro Gioè,Damiano Arciuolo,Maria Rita Carbone,Gianfranco Zannoni,Maria Antonietta Gambacorta,Giulio Maccauro,Giovanni Scambia,Giacomo Corrado
标识
DOI:10.4103/jcrt.jcrt_9_20
摘要
There are a few reported cases of isolated localized metastasis to bone arising from cancer of uterine cervix in the literature. This is a case of uterine cervix cancer with isolated metastasis to the humerus. A 57-year-old female with a diagnosis of FIGO Stage IIB invasive squamous cell carcinoma of uterine cervix underwent neoadjuvant chemoradiation therapy (CRT) and radical surgery with complete pathological response. Nine months after the surgery, a total body positron emission tomography/computed tomography (PET/CT) scan documented a lesion localized in the proximal part of the right humerus, whereas no evidence of skeletal metastasis found elsewhere. The biopsy from the bone lesion showed a metastatic squamous cell carcinoma of the uterine cervix. A surgical excision of the humeral lesion plus chemotherapy and zoledronic acid was performed. After 9 months, the patient experienced liver metastases and died 2 months later. Bone metastasis is not so infrequent in patients with locally advanced cervical cancer. Total body PET/CT scan should be included in staging work up, and an appropriate treatment should have the primary objective of quality of life preservation.
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