The Conceptual Development of a Conjunctive Olefination

Abstract We recently discovered a functional group tolerant and transition-metal-free conjunctive olefination reaction with applications in late-stage functionalization chemistry. In this Synpacts contribution, we analyze the conceptual background that has stimulated the discovery of this reactivity and reflect on the key aspects of its development. 1 Introduction 2 Conceptual Background 2.1 Photoredox-Mediated Giese Reaction 2.2 Photoredox Radical-Polar Reactivity 3 The Development of the Process 4 Conclusion