接种疫苗
最优控制
流行病模型
数学
订单(交换)
分叉
理论(学习稳定性)
控制理论(社会学)
应用数学
数学优化
控制(管理)
计算机科学
医学
物理
非线性系统
经济
人口
环境卫生
财务
量子力学
机器学习
人工智能
免疫学
作者
Xinshu Cui,Dingyu Xue,Feng Pan
标识
DOI:10.1140/epjp/s13360-022-02810-8
摘要
This paper studies a fractional-order delayed susceptible–infected–recovered epidemic model with saturated incidence rate and saturated treatment function. In particular, the positivity and boundedness of all solutions are determined. The existence and stability of all possible equilibria are also discussed. The study reveals that the model has multiple equilibria and the possible existence of backward bifurcation whose implications for the spread of disease are discussed. Then, a fractional-order delayed optimal control problem related to vaccination and treatment enhancement is proposed and analyzed. The existence of an optimal pair is shown and the optimal control solution is characterized. Three control strategies (viz., vaccination only; treatment enhancement only; the combination of vaccination and treatment enhancement) are discussed and compared through numerical simulations. In terms of the control effect and cost, the combination of vaccination and treatment enhancement is significantly superior to vaccination, and vaccination is better than treatment enhancement.
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