适体
纳米技术
蛋白质检测
生物传感器
计算生物学
C反应蛋白
计算机科学
医学
材料科学
生物
炎症
免疫学
分子生物学
作者
Ming-Qing Tang,Jing Xie,Liangming Rao,Ya-Jie Kan,Pei Luo,Lin‐Sen Qing
标识
DOI:10.1007/s00216-021-03674-0
摘要
C-reactive protein (CRP), a non-specific acute-phase indicator of inflammation, has been widely recognized for its value in clinical diagnostic applications. With the advancement of testing technologies, there have been many reports on fast, simple, and reliable methods for CRP testing. Among these, the aptamer-based biosensors are the focus and hotspot of research for achieving high-sensitivity analysis of CRP. This review summarizes the progress of in vitro aptamer screening for CRP and the recent advances in aptamer-based CRP sensor applications, thus developing insight for the new CRP aptasensor design strategy.
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