Outcomes of reproduction following cesarean scar pregnancy treatment: A systematic review and meta-analysis

医学 怀孕 流产 产科 科克伦图书馆 活产 荟萃分析 生育率 异位妊娠 梅德林 妊娠率 妇科 人口 内科学 法学 环境卫生 生物 遗传学 政治学
作者
Jiawen Wu,Jianbin Ye,Zhenbo OuYang,Zixian Wan,Qiushi Zhang,Biting Zhong,Shiyuan Wei
出处
期刊:European Journal of Obstetrics & Gynecology and Reproductive Biology [Elsevier BV]
卷期号:262: 80-92 被引量:22
标识
DOI:10.1016/j.ejogrb.2021.05.010
摘要

Objectives To explore the reproductive outcomes of women with a history of cesarean scar pregnancy (CSP) and the influence of various treatments on subsequent pregnancy outcomes. Study design The PubMed, Embase, Medline, Cochrane Library and ClinicalTrial.gov databases were searched for studies with the outcomes of pregnancy after CSP treatment. Studies that reported reproductive outcomes after CSP with more than 5 followed cases were included. The main data collected includes the treatment methods of CSP and subsequent pregnancy outcomes. The main information includes intrauterine pregnancy, recurrent CSP (RCSP), and spontaneous miscarriage, while the secondary information includes complications during pregnancies and the outcomes of childbirths. According to different treatments (conservative treatment, surgical treatment without resection of cesarean scar, and surgical treatment with resection of cesarean scar), a stratified analysis was carried out to compare the influence of treatments on subsequent pregnancy outcomes. Results A total of 32 studies including 3380 cases of CSP met the inclusion criteria, of which 583 cases conceived again after treatment (including 292 cases of unexpected pregnancy), and finally 178 cases delivered successfully. The follow-up time ranged from 3 to 72 months. Among women with fertility requirements, a total of 291 cases in 403 women were successfully conceived during the follow-up period in 15 studies. Thence the pregnancy rate of women with fertility requirements was 76.2 %. Among all of the 583 successfully conceived women, 83.4 % of them had intrauterine pregnancy, while 15.3 % of cases were RCSP. The total ectopic pregnancy rate reached 16.6 %, covering RCSP and other sites of ectopic pregnancy. 14.6 % of intrauterine pregnancy experienced spontaneous miscarriage. The intrauterine pregnancy rates of the conservative treatment group, the surgical treatment without resection of cesarean scar group, and the surgical treatment with resection of cesarean scar group were 93.1 %, 80.1 % and 86.0 % respectively; the corresponding RCSP rates were 6.9 %, 15.6 % and 14.0 % respectively; and the corresponding spontaneous miscarriage rates were 20.7 %, 13.9 % and 22.2 % respectively. Conclusion The outcomes of reproduction after CSP included intrauterine pregnancy, RCSP and other sites of ectopic pregnancy. Women with a history of CSP still have a high pregnancy rate, but the risk of RCSP and spontaneous miscarriage is also increased. It is impossible to clarify the effect of different treatments on subsequent pregnancy. Whether the resection and repair of cesarean scar can ameliorate reproductive outcomes needs to be further assessed. Further large-scale prospective studies, even RCTs with long-term follow-up are needed to expound the outcomes of reproduction after CSP and the effect of different treatments on subsequent reproductive outcomes.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
1秒前
可爱的函函应助徐嘿嘿采纳,获得10
2秒前
2秒前
轻松惜筠发布了新的文献求助10
3秒前
3秒前
AJian发布了新的文献求助10
4秒前
cgliuhx发布了新的文献求助10
5秒前
Cxxxx完成签到 ,获得积分10
6秒前
7秒前
8秒前
肉丸子完成签到,获得积分10
8秒前
木木林发布了新的文献求助10
8秒前
9秒前
SYLH应助你怎么睡得着觉采纳,获得10
9秒前
干饭大王应助热心小松鼠采纳,获得10
10秒前
13秒前
13秒前
成就猫咪发布了新的文献求助10
14秒前
lppp完成签到,获得积分10
14秒前
璇璇完成签到 ,获得积分10
14秒前
辽阳太子完成签到,获得积分10
16秒前
16秒前
无糖乐发布了新的文献求助10
16秒前
風衣完成签到,获得积分20
17秒前
Ander完成签到 ,获得积分10
17秒前
lppp发布了新的文献求助10
19秒前
夹谷蕈完成签到 ,获得积分10
19秒前
cryjslong完成签到,获得积分10
21秒前
24秒前
木木发布了新的文献求助10
25秒前
共享精神应助辽阳太子采纳,获得10
26秒前
SYLH应助你怎么睡得着觉采纳,获得10
26秒前
27秒前
马敏完成签到 ,获得积分10
27秒前
fengzi151发布了新的文献求助10
27秒前
Liyipu发布了新的文献求助10
28秒前
30秒前
烟花应助Lice采纳,获得10
31秒前
31秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Cognitive Neuroscience: The Biology of the Mind 1000
Technical Brochure TB 814: LPIT applications in HV gas insulated switchgear 1000
Immigrant Incorporation in East Asian Democracies 600
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
A Preliminary Study on Correlation Between Independent Components of Facial Thermal Images and Subjective Assessment of Chronic Stress 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3966822
求助须知:如何正确求助?哪些是违规求助? 3512333
关于积分的说明 11162715
捐赠科研通 3247203
什么是DOI,文献DOI怎么找? 1793730
邀请新用户注册赠送积分活动 874602
科研通“疑难数据库(出版商)”最低求助积分说明 804432