检查表
孟德尔遗传
观察研究
背景(考古学)
孟德尔随机化
心理学
医学
认知心理学
遗传变异
生物
遗传学
病理
基因
基因型
古生物学
作者
Neil M Davies,Michael V. Holmes,George Davey Smith
出处
期刊:BMJ
[BMJ]
日期:2018-07-12
卷期号:: k601-k601
被引量:2584
摘要
Mendelian randomisation uses genetic variation as a natural experiment to investigate the causal relations between potentially modifiable risk factors and health outcomes in observational data. As with all epidemiological approaches, findings from Mendelian randomisation studies depend on specific assumptions. We provide explanations of the information typically reported in Mendelian randomisation studies that can be used to assess the plausibility of these assumptions and guidance on how to interpret findings from Mendelian randomisation studies in the context of other sources of evidence
科研通智能强力驱动
Strongly Powered by AbleSci AI