离子导入
医学
癌症
视网膜母细胞瘤
胰腺癌
药物输送
癌症治疗
癌症治疗
重症监护医学
内科学
纳米技术
生物化学
基因
放射科
化学
材料科学
作者
James Byrne,Jen Jen Yeh,Joseph M. DeSimone
标识
DOI:10.1016/j.jconrel.2018.06.020
摘要
Despite major advancements in cancer treatments, there are still many limitations to therapy including off-target effects, drug resistance, and control of cancer-related symptoms. There are opportunities for local drug delivery devices to intervene at various stages of cancer to provide curative and palliative benefit. Iontophoretic devices that deliver drugs locally to a region of interest have been adapted for the treatment of cancer. These devices have shown promise in pre-clinical and clinical studies for retinoblastoma, skin, bladder, and pancreatic cancers. Herein, we review iontophoretic devices used in the management of cancer.
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