接种疫苗
结合疫苗
病毒学
肺炎链球菌
结合
血清型
免疫
肺炎球菌疫苗
脑膜炎
作者
Jinfu Xie,Yuhua Zhang,Ivette Caro-Aguilar,Lani Indrawati,William J. Smith,Cecilia Giovarelli,Michael A. Winters,John E. Macnair,Jian He,Chitrananda Abeygunawardana,Luwy Musey,Kosinski Michael J,Julie M. Skinner
出处
期刊:Pediatric Infectious Disease Journal
[Ovid Technologies (Wolters Kluwer)]
日期:2020-01-01
卷期号:39 (1): 70-77
被引量:7
标识
DOI:10.1097/inf.0000000000002522
摘要
Background:Evaluation of a pneumococcal conjugate vaccine (PCV) in an animal model provides an initial assessment of the performance of the vaccine prior to evaluation in humans. Cost, availability, study duration, cross-reactivity and applicability to humans are several factors which contribute to
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