脱碳
镍
催化作用
硅烷化
化学
配体(生物化学)
药物化学
有机化学
受体
生物化学
作者
Syun Nakatani,Yuri Ito,Shun Sakurai,Takuya Kodama,Mamoru Tobisu
标识
DOI:10.1021/acs.joc.0c00772
摘要
Nickel-catalyzed decarbonylation of acylsilanes is developed. In sharp contrast to cross-coupling reactions of acylsilanes, in which the silyl group serves as a leaving group, the silyl group is retained in the product in this decarbonylation reaction. Although the strong binding of the dissociated CO to the nickel center frequently hinders catalyst turnover in nickel-mediated decarbonylative reactions, this reaction can be catalyzed by nickel complexes bearing a CO ligand.
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