Allele specific knock-down of human P23H rhodopsin mRNA and prevention of retinal degeneration in humanized P23H rhodopsin knock-in mouse, following treatment with an intravitreal GAPmer antisense oligonucleotide (QR-1123)
视紫红质
视网膜变性
寡核苷酸
基因敲除
分子生物学
生物
视网膜
基因
遗传学
生物化学
作者
Patricia Biasutto,Peter Adamson,Kalyan Dulla,Sue Murray,Brett P. Monia,Michael L. McCaleb