蛋白质组学
中医药
计算生物学
蛋白质组
药物发现
传统医学
化学
医学
药物开发
作者
Zhi-Hua Yuan,Xiao Yu,Ya-di Duan,Peng Liu,Yan-Yan Jiang,Wei Zhang,Bin Liu
出处
期刊:China journal of Chinese materia medica
[China Journal of Chinese Materia Medica]
日期:2020-03-01
卷期号:45 (5): 1034-1038
标识
DOI:10.19540/j.cnki.cjcmm.20191206.201
摘要
The study on the targets of traditional Chinese medicine is an important part of researchers using modern scientific language to clarify the mechanism of traditional Chinese medicine. However, the research on the targets of Chinese medicine is full of challenges due to the complexity of active ingredients. As a branch of systems biology, proteomics focus on specific proteins in living organisms from a holistic perspective, which significantly improves the efficiency of targets discovery and has obvious advantages in the research of targets of Chinese medicine. Based on relevant literature and different methods used in targets of Chinese medicine, proteomics can be divided into chemical proteomics, differential proteomics and quantitative proteomics. The applications of the above three methods are illustrated in this paper as well, which will provide new methods and ideas for the study of the mechanism of Chinese medicine in the future.
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