化学
侧链
吡咯烷
烷基化
连接器
烷基
雌激素受体
立体化学
受体
生物化学
有机化学
内科学
聚合物
医学
癌症
乳腺癌
计算机科学
操作系统
催化作用
作者
Timothy A. Blizzard,Frank DiNinno,Jerry D. Morgan,Helen Y. Chen,Jane Y. Wu,Seongkon Kim,Wanda Chan,Elizabeth T. Birzin,Yi Yang,Lee-Yuh Pai,Paula M.D. Fitzgerald,Nandini Sharma,Ying Li,Zhoupeng Zhang,Edward C. Hayes,Carolyn DaSilva,Wei Tang,Susan P. Rohrer,James M. Schaeffer,Milton L. Hammond
标识
DOI:10.1016/j.bmcl.2004.10.036
摘要
A series of dihydrobenzoxathiin SERAMs with alkylated pyrrolidine side chains or alkylated linkers was prepared. Minor modifications in the side chain or linker resulted in significant effects on biological activity, especially in uterine tissue.
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