Estimation of cognitive impairment in chronic pain patients and characteristics of estimated mild cognitive impairment

医学 慢性疼痛 认知 物理疗法 生活质量(医疗保健) 痴呆 日常生活活动 蒙特利尔认知评估 疼痛评估 焦虑 认知障碍 内科学 精神科 护理部 疾病 疼痛管理
作者
Masamichi Moriya,Lingyun Hu,Kaoru Sakatani,Masaki Kitahara
出处
期刊:Frontiers in Neurology [Frontiers Media]
卷期号:15
标识
DOI:10.3389/fneur.2024.1344190
摘要

Background Patients with chronic pain suffer from psychological effects such as anxiety due to the pain itself. Pain can not only impair activities of daily living (ADL) and quality of life (QOL), but also impair cognitive function. Therefore, in this study, we aimed to estimate the cognitive function of chronic pain patients using a deep neural network (DNN) model that has already been implemented in society. We investigated the characteristics of patients presumed to have mild cognitive impairment (MCI) and, at the same time, verified the relationship with the questionnaire commonly used in chronic pain research, which is administered by 43 university affiliated hospitals and medical institutions participating in the chronic pain research group of the Ministry of Health, Labor and Welfare in Japan (assessment batteries). Method The study included 114 outpatients from a multidisciplinary pain clinic, and we estimated their Mini-Mental State Examination (MMSE) scores based on age and basic blood test data (23 items). Furthermore, we classified the estimated MMSE scores of chronic pain patients into two groups based on a cutoff score of 27, which indicates MCI, and compared the blood data and assessment batteries. Additionally, we used a control group of 252 healthy adults aged 45 years or older who visited a dementia prevention outpatient clinic for comparison with the MMSE scores of chronic pain patients. Result The MMSE scores in chronic pain patients were below the cutoff for MCI. When classified into two groups based on the estimated MMSE score of 27 points, WBC, RBC, Hb, Hct, PLT, UA, BUN, creatinine, Triglyceride, and γ-GT were significantly higher in the blood data. In the MCI group, PDAS values were significantly lower. Furthermore, only in the non-MCI group, a significant correlation was found between the estimated MMSE value and BPI, PDAS, and Locomo. The estimated MMSE scores were significantly lower in chronic pain patients than in healthy adults ( p = 0.04). Conclusion Patients with chronic pain may exhibit cognitive impairment due to systemic metabolic disturbances. This suggests that chronic pain affects activities of daily living, resulting in systemic metabolic disorders.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
秋天里的水完成签到,获得积分10
4秒前
wxy完成签到,获得积分10
5秒前
6秒前
香蕉觅云应助儒雅南风采纳,获得10
8秒前
郭小宝发布了新的文献求助10
12秒前
情怀应助幸福大白采纳,获得10
12秒前
齐天大圣应助幸福大白采纳,获得30
13秒前
孙燕应助幸福大白采纳,获得30
13秒前
英姑应助幸福大白采纳,获得30
13秒前
13秒前
Hashub完成签到,获得积分20
13秒前
15秒前
xueyu发布了新的文献求助10
17秒前
wonder123发布了新的文献求助10
18秒前
科研通AI2S应助张雯思采纳,获得10
19秒前
19秒前
小二郎应助张雯思采纳,获得10
19秒前
情怀应助张雯思采纳,获得10
19秒前
19秒前
科研通AI2S应助张雯思采纳,获得10
19秒前
今后应助张雯思采纳,获得10
19秒前
在水一方应助张雯思采纳,获得10
19秒前
Jasper应助张雯思采纳,获得10
19秒前
41应助张雯思采纳,获得10
19秒前
19秒前
新xin完成签到,获得积分10
20秒前
儒雅南风发布了新的文献求助10
20秒前
xxddw发布了新的文献求助10
20秒前
33发布了新的文献求助30
20秒前
21秒前
21秒前
Rondab应助科研小白采纳,获得10
22秒前
23秒前
wonder123完成签到,获得积分10
23秒前
量子星尘发布了新的文献求助10
25秒前
幸福的乾发布了新的文献求助10
25秒前
xyj6486发布了新的文献求助10
25秒前
26秒前
小晓发布了新的文献求助10
28秒前
Owen应助伏坎采纳,获得10
31秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3989444
求助须知:如何正确求助?哪些是违规求助? 3531531
关于积分的说明 11254250
捐赠科研通 3270191
什么是DOI,文献DOI怎么找? 1804901
邀请新用户注册赠送积分活动 882105
科研通“疑难数据库(出版商)”最低求助积分说明 809174