Accuracy of intraoral scanners for static virtual articulation: A systematic review and meta-analysis of multiple outcomes

Statement of problem Static virtual articulation with intraoral scanners (IOSs) can eliminate the human errors related to conventional articulation methods and enhance accuracy. A systematic review and meta-analysis based on multiple accuracy outcomes can combine the available literature and provide an evidence-based conclusion. Purpose The purpose of this systematic review and meta-analysis was to investigate whether static virtual articulation with IOSs has acceptable accuracy for completely dentate and partially edentulous patients. Material and methods An electronic search was conducted on the PubMed, Web of Science, and Scopus databases. In addition, a manual search through reference lists of selected articles was performed. Clinical and in vitro studies evaluating the accuracy of static virtual articulation with IOSs based on diagnostic accuracy, trueness, precision, and occlusion of fabricated fixed restorations were included. The pooled results included sensitivity, specificity, positive likelihood ratio (+LR), negative likelihood ratio (-LR), diagnostic odds ratios (DORs), mean values, and 95% confidence intervals (CIs). Results were presented as forest plots. The summary receiver operator characteristic (SROC) was displayed to summarize the diagnostic test performance. Results The initial search resulted in a total of 5061 articles, of which 29 articles were included in the analysis. The virtual interocclusal records (VIRs) with IOSs showed acceptable pooled results for diagnostic accuracy (sensitivity: 0.76; specificity: 0.80; DOR: 14.77, area under the SROC (AUC): 0.87; cut off point Q∗: 80; +LR: 3.66; -LR: 0.31). The pooled data for trueness and precision were within the acceptable limits. The pooled mean (95% CI) for trueness based on linear deviations was 243.53 (144.90, 342.17). The pooled mean (95% CI) for precision based on 3D deviation of articulated models was 54.97 (43.49, 66.46). In addition, the included studies reported accurate occlusion for fixed restorations fabricated by using VIRs with IOSs. Moreover, most of the studies on trueness based on virtual occlusal contact area reported acceptable accuracy. Conclusions VIRs with IOSs had acceptable accuracy for static virtual articulation.