生物
葡萄糖稳态
平衡
选择性拼接
小岛
胰岛
RNA剪接
胰岛素
基因
糖尿病
分泌物
细胞生物学
内分泌学
遗传学
胰岛素抵抗
核糖核酸
信使核糖核酸
作者
Kristle Garcia,Anna L. Gloyn
标识
DOI:10.1016/j.tig.2023.04.003
摘要
Many molecular mechanisms underlying blood glucose homeostasis remain elusive. Juan-Mateu et al. find that pancreatic islet cells utilize a regulatory program, originally identified in neurons, that involves alternative splicing of microexons in genes important for insulin secretion or diabetes risk.
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