The recent study by Adriana Roca-Fernandez et al.1 published in the Journal of Hepatology was read with keen interest. This research, which delved into the association between liver disease and significant cardiovascular outcomes using the UK Biobank data, stands out for its comprehensive approach and the valuable insights provided. The primary findings, highlighting the role of liver disease as a potential risk factor for cardiovascular diseases (CVD) events, are both timely and of great significance.