Green Construction of Magnetic Azo Porous Organic Polymer for Highly Efficient Enrichment and Detection of Phenolic Endocrine Disruptors

Porous organic polymers (POPs) are prominent sorbents for effective extraction of endocrine disrupting chemicals (EDCs). However, green and sustainable construction of functional POPs is still challenging. Herein, using hydroxy-rich natural kaempferol and low toxic basic fuchsin as monomers, a magnetic azo POP (Mazo-POP) was developed by diazo coupling reaction for the first time. The Mazo-POP presented excellent extraction ability for endocrine disrupting chemicals (EDCs) with phenolic structure, and therefore it was served as magnetic sorbent to extract phenolic EDCs from water and fish samples, followed by ultrahigh performance liquid chromatography-tandem mass spectrometric detection. The Mazo-POP based analytical method afforded a good linearity of 0.06-100 ng mL-1 and 0.3-500 ng g-1 for water and fish samples respectively, with detection limits (S/N=3) of 0.02-0.5 ng mL-1 and 0.1-1.5 ng g-1, respectively. The method recovery was from 85.2% to 109% and relative standard deviation was less 5.3%. Moreover, the effective adsorption was mainly contributed by hydrogen bond, π-π interaction, pore filling and hydrophobic interaction. This work not only provides an efficient method for sensitive determination of phenolic EDCs, but also highlights the significance of green preparation of environmentally friendly sorbents for enriching/adsorbing pollutants.