Graphene-wrapped WO3/Mo derivatives for the simultaneous electrochemical detection of dopamine and uric acid

We report the synthesis of tungsten oxide/Mo-derivatives incorporated graphene, h-WO3/MoO3/MoS2/rGO nanocomposite as an efficient electrocatalyst for the simultaneous determination of DA and UA. The composite was prepared via the simple hydrothermal method which invoked interesting morphological and structural changes to the composite’s components that were explored using the XRD, Raman, XPS and TEM characterization techniques. Under optimized conditions, the electroanalytical quantification in DPV exhibited two wide linear ranges of 1.25–194 µM and 244–495 µM for DA detection and a broad linear response of 10–1330 µM for UA detection. The LOD was found to be 0.539 µM and 2.402 µM for DA and UA respectively. The sensor’s anti-interference, repeatability, reproducibility and stability properties were also evaluated. Finally, the applicability in simultaneous detection of DA and UA in RT samples of human blood and urine samples were also successfully assessed whose results validates the sensor’s reliability.