光热治疗
材料科学
纳米材料
光动力疗法
生物相容性
碳纳米管
纳米复合材料
纳米技术
光热效应
化学
有机化学
冶金
作者
Yu Meng,Congcong Wang,Lijie Song,Zewen Su,Yaojun Jiang,Yanbang Lian,Gongxun Bai,Qingxia Fan
标识
DOI:10.1016/j.matdes.2023.112201
摘要
The use of functional nanomaterials to realize tumor therapeutic therapy has received considerable attention. However, a single type of nanomaterial usually can only achieve one specific function, and may cause biosafety problems due to poor metabolism. In this work, we have designed a kind of nanocomposite film based on Bi2Se3 nanosheets and carbon nanotubes, which can achieve efficient photothermal conversion and reactive oxygen species generation under near-infrared laser irradiation. Moreover, the developed films showed good biocompatibility in vivo. The multifunctional films showed remarkable therapeutic effects under 808 nm excitation with 0.3 W/cm2, which avoiding the introduction of nano-reagents into the mice and excessive laser power damage. Our work will provide reference for the use of nanomaterials with heterojunctions in synergistic therapy strategies of photothermal and photodynamic therapy.
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