Advances in the Chemical Components and Pharmacological Effects of Paederia Scandens

Paederia scandens (L.) Merr., commonly known as 'ji shi teng' in traditional Chinese medicine, has garnered attention for its medicinal benefits. This review synthesizes the research on its chemical constituents—iridoids, flavonoids, triterpenoids, and essential oils—and their pharmacological effects, including anti-inflammatory, analgesic, gastroprotective, and antioxidant activities. Despite promising pharmacological profiles, the clinical applications of this herb are still limited, highlighting the need for further clinical trials and pharmacokinetic studies. This paper emphasizes the integration of traditional herbal medicine with modern research to fully explore the therapeutic potential of Paederia scandens.