纳米技术
生物相容性
药物输送
超分子化学
材料科学
癌症治疗
背景(考古学)
涂层
生物医学工程
癌症
工程类
化学
医学
有机化学
晶体结构
冶金
内科学
古生物学
生物
作者
Yijie Li,Yijie Li,Yijie Li,Yijie Li,Yijie Li
标识
DOI:10.1088/1748-605x/ad49f4
摘要
Abstract Supramolecular chemistry is versatile for developing stimuli-responsive, dynamic and multifunctional structures. In the context of biomedical engineering applications, supramolecular assemblies are particularly useful as coatings for they can closely mimic the natural structure and organisation of the extracellular matrix (ECM), they can also fabricate other complex systems like drug delivery systems and bioinks. In the current context of growing medical device-associated complications and the developments in the controlled drug delivery and regenerative medicine fields,supramolecular assemblies are becoming an indispensable part of the biomedical engineering arsenal. This review covers the different supramolecular assemblies in different biomedical applications with a specific focus on antimicrobial coatings, coatings that enhance biocompatibility, surface modifications on implantable medical devices, systems that promote therapeutic efficiency in cancer therapy, and the development in bioinks. The introduced supramolecularsystems include multilayer coating by polyelectrolytes, polymers incorporated with nanoparticles, coating simulation of ECM, and drug delivery systems. A perspective on the application of supramolecular systems is also included.
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