Lab‐on‐a‐chip: Opportunities for chemical engineering

AIChE JournalVolume 48, Issue 8 p. 1590-1595 Perspective Lab-on-a-chip: Opportunities for chemical engineering Andrea W. Chow, Andrea W. Chow Caliper Technologies Corp., Mountain View, CA 94043Search for more papers by this author Andrea W. Chow, Andrea W. Chow Caliper Technologies Corp., Mountain View, CA 94043Search for more papers by this author First published: 16 April 2004 https://doi.org/10.1002/aic.690480802Citations: 102AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Literature Cited Bousse, L., C. Cohen, T. Nikiforov, A. Chow, A. R. Kopf-Sill, R. Dubrow, and J. W. Parce, "Electrokinetically Controlled Microfluidic Analysis Systems," Ann. Rev. Biophys. Biomol. Struct., 29, 155 (2000). Brenner, H., and E. A. Edwards, Macrotransport Processes, Butterworth-Heinemann, Boston (1993). de Mello, A. J., "Chip-MS: Coupling the Large with the Small," Lab Chip, 1, 7N (2001). Duffy, D. C., J. C. McDonald, O. J. A. Schueller, and G. M. Whitesides, "Rapid Prototyping of Microfluidic Systems in Poly(dimethylsiloxane)," Anal. Chem., 70, 4974 (1998). Effenhauser, C. S., G. J. M. Briun, A. Paulus, and M. Ehrat, "Integrated Capillary Electrophoresis on Flexible Silicone Microdevices: Analysis of DNA Restriction Fragments and Detection of single DNA Molecules on Microchips," Anal. Chem., 69, 3451 (1997). Gravesen, P., J. Branebjerg, and O. S. Jensen, "Microfluidics-A Review," J. Micromech. Microeng., 3, 168 (1993). Harrison, D. J., A. Manz, Z. Fan, H. Ludi, and H. M. Widmer, "Capillary Electrophoresis and Sample Injection Systems Integrated on a Planar Glass Chip," Anal. Chem., 64, 1926 (1992). Jacobson, S. C., R. Hergenroder, L. B. Koutny, R. J. Warmack, and J. M. Ramsey, "Effects of Injection Schemes and Column Geometry on the Performance of Microchip Electrophoresis Devices," Anal. Chem., 66, 1107 (1994). Jensen, K. F., "Microchemical Systems: Status, Challenges, and Opportunities," AIChE J., 45, 2051 (1999). Kopf-Sill, A. R., A. W. Chow, L. Bousee, and C. B. Cohen, " Creating a Lab-on-a-Chip with Microfluidic Technologies," book chapter in Integrated Microfabricated Biodevices, M. J. Heller and A. Guttman, eds., Marcel Dekker, New York (2001). Kricka, L. J., P. Fortina, J. J. Panaro, P. Wilding, G. Alonso-Amigo, and H. Becker, "Fabrication of Plastic Microchips by Hot Embossing," Lab Chip, 2, 1 (2002). Manz, A., N. Grabber, and H. M. Widmer, "Miniaturized Total Chemical Analysis Systems: a Novel Concept for Chemical Sensing," Sens. Acutators B, 1, 244 (1990). McCormick, R. M., R. J. Nelson, M. G. Alonso-Amigo, D. J. Benvegnu, and H. H. Hooper, "Microchannel Electrophoretic Separations of DNA in Injection-Molded Plastic Substrates," Anal. Chem., 69, 2626 (1997). Mrksich, M. and G. M. Whitesides, "Patterning Self-Assembled Monolayers Using Microcontact Printing: A New Technology for Biosensors," Trends Biotechnol, 13, 228 (1995). Reyes, D. R., D. Iossifidis, P.-A. Aurous, and A. Manz, "Micro Total Analysis Systems. 1. Introduction, Theory, and Technology," Anal. Chem., 74, 2623 (2002). Sanders, G. H. W., and A. Manz, "Chip Based Microsystems for Genomic and Proteomic Analysis," Trends Anal. Chem., 19, 364 (2000). Sittampalam, G., S. Kahl, and W. Janzen, "High-Throughtput Screening: Advances in Assay Technologies," Curr. Opin, Chem. Bio., 1, 384 (1997). Stone, H. A., and S. Kim, "Microfluidics: Basic Issues, Applications, and Challenges," AIChE J., 47, 1250 (2001). Terry, S. C., "A Gas Chromatography System Fabricated on a Silicon Wafer using Integrated Circuit Technology," PhD Diss. Stanford University (1975). Troian, S. M. and D. E. Kataoka, "Patterning Liquid Flow at the Micron Scale," Nature, 402, 794 (1999). Unger, M. A., H.-P. Chou, T. Thorsen, A. Scherer, and S. R. Quake, "Monolithic Microfabricated Valves and Pumps by Multilayer Soft Lithography," Science, 288, 113 (2000). Zhao, B. J., S. Moore, and D. J. Beebe, "Surface-Directed Liquid Flow Inside Microchannels," Science, 291, 1023 (2001). Citing Literature Volume48, Issue8August 2002Pages 1590-1595 ReferencesRelatedInformation